diff --git a/Makefile b/Makefile
index cf88a72..715370e 100644
--- a/Makefile
+++ b/Makefile
@@ -148,6 +148,9 @@ ifeq ($(shell $(CC) -o /dev/null compat/test-closefrom.c 2>/dev/null && echo 1),
 DEFINES+=-DHAVE_CLOSEFROM
 endif
 endif
+ifdef CONFIG_NO_WORKER
+DEFINES+=-DCONFIG_NO_WORKER
+endif
 
 CFLAGS+=$(DEFINES)
 CFLAGS_DEBUG=$(CFLAGS) -O0
diff --git a/quickjs-libc.c b/quickjs-libc.c
index 141f79f..93e0d06 100644
--- a/quickjs-libc.c
+++ b/quickjs-libc.c
@@ -64,7 +64,7 @@ typedef sig_t sighandler_t;
 
 #endif
 
-#if !defined(_WIN32)
+#if !defined(_WIN32) && !defined(CONFIG_NO_WORKER)
 /* enable the os.Worker API. IT relies on POSIX threads */
 #define USE_WORKER
 #endif
diff --git a/quickjs.c b/quickjs.c
index 642ae34..0d78919 100644
--- a/quickjs.c
+++ b/quickjs.c
@@ -68,7 +68,7 @@
 
 /* define to include Atomics.* operations which depend on the OS
    threads */
-#if !defined(EMSCRIPTEN)
+#if !defined(EMSCRIPTEN) && !defined(CONFIG_NO_WORKER)
 #define CONFIG_ATOMICS
 #endif